How Cardarine works?

GW-501516 is a SARM (selective androgen receptor modulator) developed for the prevention and treatment of muscular atrophy. Possibly, it is prescribed for cachexia and sarcopenia, as well as for hormone replacement therapy.

Cardarine belongs to the class of chemicals known as SARMS. SARMS creates anabolic activity in specific androgen receptors. In comparison to testosterone and other anabolic steroids, the advantage of SARMS is that they do not have androgenic activity in non-muscle tissues. Ostarine is effective in maintaining and increasing lean mass.

How it works?

SARMS binds to androgen receptors and shows anabolic activity in bone and muscle tissues.

Activation of androgen receptors

The activation of the androgenic receptors alters the expression of the genes and increases the protein synthesis, which develops the muscles. In essence, SARMS as ostarine causes muscle growth in the same way as steroids, but without stimulating the growth of the prostate and other sex organs.

Cardarine, in particular, exerts its effect on muscle tissue almost exclusively. So not only serves as a treatment for a wide range of diseases that cause loss of muscle mass (related to AIDS or cancer), but also has immense potential to develop muscle mass in bodybuilders and athletes, in addition to minimizing atrophy during recovery periods of surgeries or similar situations. You can read much more about Cardarine from this awesome Cardarine review online.


Cardarine is the most anabolic of all SARMS, so it is most commonly used in the muscle gain phase. Your total weight gains can not be compared to gross profit steroids, but all of those gains will be lean mass. Gains are relatively easy to maintain and users typically see an increase of up to 3 kg of lean mass during an 8-week course of 25 mg per day (with a high calorie diet). The most common dose is 25 mg per day for 8 weeks. The side effects found with steroids will not be present in this cycle. In general, with Cardarine, the higher the dose, the greater the suppression. Although suppression is minimal and not comparable to that caused by a steroid cycle, any Cardarine cycle lasting more than 4 weeks requires a small 3-week CPT without the need for any SERM.


Cardarine would be placed in this cycle to preserve lean mass when calories are reduced. A protocol of 15-20 mg per day for 6-8 weeks is interesting as there would be no significant side effects or suppression. However, it should be emphasized that the results would be better with S-4 SARM.